Enter the Milken-Motsepe Innovation Prize program. The program is a collaboration between the Milken Institute’s Center for Strategic Philanthropy and the Motsepe Foundation, a South Africa-based organization dedicated to tackling poverty and improving quality of life across Africa. The program’s goal is to cultivate entrepreneurship throughout the continent, marking just one of many emerging initiatives that have set its focus on Africa’s innovators and the rich potential of African economies. Click here to learn more.

News clips
$2 Million Milken-Motsepe Prize Launched to Spur AI-Driven Manufacturing in Africa
A new $2 million equity-free prize program, backed by South African billionaire Dr. Patrice Motsepe and the Milken Institute, is placing artificial intelligence and manufacturing at the heart of Africa’s technology ambitions. Unveiled at the 2025 Milken Institute Global Conference in Los Angeles, the Milken-Motsepe Prize in AI and Manufacturing marks the fourth—and most ambitious—edition in a growing series of innovation challenges designed to tackle Africa’s structural issues through technology. This round turns a sharp focus to artificial intelligence and smart manufacturing—two sectors where African participation has remained limited despite strong global momentum. Read the full article here.